How to Handle Hazardous Materials and Substances: From the Laboratory to Modern Manufacturing Environments

25/03/2026

Understanding how to handle hazardous material

Understanding how to handle hazardous materials, no matter the industry, is crucial. Modern manufacturing environments are facing increasing pressure to enhance safety and prevent contamination events.

From pharmaceuticals and chemicals to FMCG and advanced materials, manufacturers must now integrate containment into daily operations and long-term strategies. Containment is no longer an add-on, but a necessity across all industries.

In this article, we aim to provide operators with an understanding of how to handle hazardous substances and materials in laboratory and manufacturing environments.

How to Handle Hazardous Materials and Substances: From the Lab to Modern Manufacturing

When it comes to handling hazardous or potentially hazardous materials, you must understand your materials and the hierarchy of prevention. Recent OSHA European worker protection legislation has established a hierarchy of prevention:

“The hierarchy of controls supports the identification of a range of control options that tackle the problem in a more fundamental manner.”

For example, Osha Europa has created the current hierarchy of prevention, as follows:

  • “Elimination and substitution are at the top of the hierarchy of control measures. Where possible, eliminate the use of dangerous substances by changing the process or product in which the substance is used.
  • If elimination is not possible, substitute a non-hazardous or less hazardous substance for the dangerous one.
  • If a substance or process cannot be eliminated or substituted, the exposure can be prevented or reduced by technical and organisational solutions. These are, for example, control of the emission at the source (closed system or local exhaust ventilation), or reducing the number of workers exposed to the dangerous substance, and the duration and intensity of exposure.
  • By law, using PPE is the last resort where exposure cannot be adequately controlled by other means.”

Practical handling, such as engineered design and containment controls, minimises substance release and protects workers when handling hazardous materials and substances. Additionally, ensuring that the correct training, procedures, and communication are upheld supports your operators and working environments to meet the necessary regulatory standards.

These regulatory standards are crucial in minimising hazardous risks. According to Osha Europe, employers must perform workplace risk assessments for dangerous substances and prioritise collective measures that tackle risks at source.

With these measures in place, what are the key safety considerations when handling hazardous materials?

 what are the key safety considerations when handling hazardous materials?

The Key Safety Considerations When Handling Hazardous Materials

From establishing risk assessments and procedures to ensuring there are consistent hygiene and safety rules that are maintained by all members in the work environment, containment is effective. We’ve listed the top safety considerations that should be upheld in all sectors:

Risk Assessments

According to the National Library of Medicine, “by mapping out credible incident scenarios (spills, leaks, reactions, fires, explosions), organisations can plan targeted engineering controls, emergency procedures and training that reduce both acute accidents and long‑term health effects.”

Additionally, establishing consistent risk assessments that are documented ensures that employers risk fines and legal repercussions. Without these structured risk assessments, danger could leave workers, products, and the environment inadequately protected against contaminants.

Consistent Procedures, Information Instruction and Training

Once you have established a risk assessment with procedures in place, this training becomes consistent in behaviour. The ICC Council reiterates this point, stating, “organisations that invest in ongoing hazmat training typically see fewer incidents, less downtime, and lower costs from injuries, clean‑up and liability, because routine tasks are carried out consistently and correctly.”

Personal Protection Equipment (PPE)

It is generally accepted that PPE (personal protective equipment) should be the last resort when handling hazardous materials and substances. However, if you are using protective clothing, you should ensure that it has been properly inspected before use and that it fits correctly.

Now that you understand the key safety considerations when handling hazardous materials and substances, you can see how each industry uses these materials.

Common Use Cases

Each industry, from nuclear to FMCG, uses hazardous materials in everyday production. From specialised industrial applications, research and development, to flammable liquids, learn how each industry has common use cases in handling hazardous materials and substances.

  • Nuclear: Crucially, the nuclear industry works with hazardous and radioactive materials daily. These materials are used across power generation, specialised industrial applications, and medical isotope production.
  • Chemical: From synthesising products, driving industrial reactions to maintaining operational processes, the chemical industry handles flammable liquids, toxic gases, and reactive compounds to produce products and pharmaceuticals.
  • Pharmaceuticals: Used across research, development, and manufacturing across pharmaceuticals, including volatile solvents, reactive compounds, and potent APIs.
  • FMCG: Commonly used across personal care and beauty products that include aerosols and flammable liquids. Food and beverage production also includes the common use of industrial-grade cleaning chemicals that need to be contained.

How can Hosokawa provide containment solutions that mitigate exposure to hazardous materials, ensure worker health and safety and product integrity?

How can Hosokawa provide containment solutions that mitigate exposure to hazardous materials, ensure worker health and safety and product integrity?

Hosokawa Containment Solutions

Hosokawa provides secure and safe containment solutions with extensive experience delivering containment solutions across pharmaceutical, chemical, food, and advanced materials sectors.

From laminar flow booths for controlled containment and clean airflow environments, fume cupboards and cabinets that provide the safe handling of volatile and hazardous substances, to nuclear gloveboxes and specialised nuclear high-containment solutions for the nuclear industry.

Our proven expertise in designing systems that support operator safety, regulatory compliance, and process efficiency allows us to support projects from concept and testing through to full-scale implementation.

Want to learn more? Find our complete containment guide here.

Now You Know How to Handle Hazardous Substances and Materials

Hosokawa containment solutions support the handling of hazardous materials and substances across a wide range of industries, helping operators to reach peak performance and safety.

Are you ready to discover what’s possible with Hosokawa containment solutions? Explore containment solutions, or speak to our expert team today.