New Mini Cyclomix for DPI Formulations

To support R&D work for the delicate blending of DPI (dry-powder inhaler) formulations, Hosokawa Micron announce the Mini Cyclomix lab mixer capable of delivering a fully homogeneous blend, without deterioration of the particles.

To disperse the actives in the lactose, the cohesive forces between the fine particles need to be broken, requiring a certain amount of mechanical energy. If too much energy is applied however, adhesive forces between the carrier and the actives will be too high, limiting the separation during inhalation. Finding the right balance for the required mixing energy is a critical issue and calls for a very efficient mixer.

Exchangeable product bowls: 100ml, 1ltr, 2ltr

These can be easily connected to the drive unit by a bayonet ring without any special tools.

Offline filling and discharging

Detachable bowls can be filled and discharged in a separate location such as a dispensary or a glovebox. The bowl can be taken to the drive unit as a contained bowl.

Simple, efficient operation

The unit can be operated by means of an integrated touch panel. It features straightforward recipe management, data logging and data export.

The large surface area, in relation to the product volume, makes the Cyclomix a very efficient mixer compared with other high shear blenders, resulting in a homogeneous blend with a minimum input of mechanical energy.

Versatile

Because of the adjustable mixing speed and time the Mini Cyclomix is able to perform other processes like coating, bonding, rounding or densification, making it a very versatile device.